Table 1.
Characteristic | Total Population | Born after 1952 | ||
---|---|---|---|---|
No ESRD | ESRD | No ESRD | ESRD | |
N total | 5,110,934 | 8203 | 3,288,340 | 1851 |
Sex (% men) | 51.1 | 66.6a | 51.3 | 62.8a |
Mean (SD) age (yr) at the end of follow-up or ESRD | 43.5±25.4 | 57.7±18a | 28.1±16.4 | 32.9±12.3a |
Mean (SD) birth yr | 1963±28 | 1940±18a | 1980±16 | 1966±11a |
Mean (SD) age (yr) at death if first-degree relative with ESRD | 65.9±21.6 | 58.0±15.9a | ||
Mean (SD) age (yr) at death if no first-degree relative with ESRD | 69.0±19.3 | 67.1±13.5a | ||
N (%) with one or two recorded relatives | 1,204,727 (23.6) | 3222 (39.3)a | 345,087 (10.5) | 129 (7.0)a |
N (%) with three or four recorded relatives | 2,414,181 (41.9) | 3059 (37.3)a | 1,545,437 (47) | 749 (42.9)b |
N (%) with five to seven recorded relatives | 1,438,642 (28.2) | 1576 (19.2)a | 1,142,575 (34.8) | 759 (41.0)a |
N (%) with eight or more recorded relatives | 326,381 (6.4) | 346 (4.2)a | 255,241 (7.7) | 169 (9.1) |
Mean (SD) no. of recorded relatives | 4.0±2.1 | 3.4±2a | 4.5±2 | 4.8±2a |
N (%) with recorded parents | 3,664,059 (71.7) | 3020 (36.8)a | 3,238,048 (98.5) | 1805 (97.5)b |
N (%) with recorded siblings | 3,113,134 (61) | 2431 (29.6)a | 2,802,089 (85.2) | 1625 (87.8)a |
N (%) with recorded children | 3,104,798 (60.7) | 6709 (81.8)a | 1,407,960 (42.8) | 943 (51)a |
N (%) with first-degree relative with ESRD | 26,733 (0.5) | 313 (3.8)a | 17,983 (0.6) | 164 (8.7)a |
N (%) with one or two parents with ESRD | 16,601 (0.3) | 110 (1.3)a | 14,267 (0.4) | 82 (4.4)a |
N (%) with one to three siblings with ESRD | 4879 (0.1) | 124 (1.5)a | 3491 (0.1) | 85 (4.6)a |
N (%) with one to three children with ESRD | 5421 (0.1) | 92 (1.1)a | 379 (0.01) | 6 (0.03)a |
N (%) with first-degree relative with ESRD caused by glomerular disease | 8724 (0.2) | 76 (0.9)a | 5795 (0.2) | 36 (1.9)a |
N (%) with first-degree relative with ESRD caused by interstitial nephritis | 2787 (0.05) | 22 (0.3)a | 1856 (0.06) | 17 (0.9)a |
N (%) with first-degree relative with ESRD caused by hereditary diseases | 3169 (0.06) | 168 (2.0)a | 2303 (0.07) | 89 (4.8)a |
N (%) with first-degree relative with ESRD caused by diabetes | 3941 (0.08) | 18 (0.2)a | 2443 (0.07) | 11 (0.6)a |
N (%) with first-degree relative with ESRD caused by hypertension | 4613 (0.09) | 20 (0.2)a | 3261 (0.1) | 10 (0.5)a |
N (%) with first-degree relative with ESRD caused by other disease | 2726 (0.05) | 6 (0.1) | 1851 (0.06) | 1 (0.05) |
P<0.001 for the comparison between ESRD and no ESRD groups.
P<0.01 for the comparison between ESRD and no ESRD groups.