Table 3.
Variable | Reduced Model | ||
---|---|---|---|
Odds Ratio | 95% Confidence Interval | P Value | |
Facility level | |||
Phosphate average (per 0.5-mmol/L increase) | 0.26 | 0.17 to 0.39 | <0.001 |
Patient level | |||
Women | 1.78 | 1.68 to 1.87 | <0.001 |
Body mass index | 0.99 | 0.99 to 1.00 | <0.001 |
Hemoglobin (per 1-g/L increase) | 1.01 | 1.01 to 1.01 | <0.001 |
Phosphate (per 0.5-mmol/L increase) | 0.45 | 0.43 to 0.46 | <0.001 |
Peripheral vascular disease | 1.24 | 1.16 to 1.33 | <0.001 |
Acute coronary syndrome | 1.16 | 1.08 to 1.24 | <0.001 |
Pulmonary edema | 1.51 | 1.41 to 1.61 | <0.001 |
Chronic obstructive pulmonary disease | 1.16 | 1.07 to 1.25 | <0.001 |
Diabetes mellitus | 1.43 | 1.31 to 1.56 | <0.001 |
Hypertension | 0.84 | 0.78 to 0.91 | <0.001 |
Serious illness | 1.31 | 1.21 to 1.41 | <0.001 |
Coronary artery bypass graft | 1.27 | 1.17 to 1.37 | <0.001 |
Peritoneal dialysis | 1.15 | 1.07 to 1.23 | <0.001 |
Predialysis care>30 d | 1.28 | 1.19 to 1.38 | <0.001 |
Distance from facility (km) | |||
<50 (referent) | |||
50–150 | 0.90 | 0.84 to 0.98 | 0.02 |
>150 | 0.89 | 0.80 to 0.99 | 0.05 |
Cause of ESRD | |||
Hypertension (referent) | |||
Diabetes | 0.96 | 0.87 to 1.06 | 0.39 |
GN | 0.76 | 0.69 to 0.84 | <0.001 |
Obstruction | 0.78 | 0.65 to 0.93 | 0.01 |
Interstitial | 0.86 | 0.73 to 1.02 | 0.09 |
PCKD | 0.50 | 0.43 to 0.58 | <0.001 |
Other | 0.94 | 0.85 to 1.04 | 0.24 |
Unknown | 0.95 | 0.85 to 1.06 | 0.37 |
Race | |||
Caucasian (referent) | |||
Asian | 0.61 | 0.54 to 0.69 | <0.001 |
Black | 0.97 | 0.83 to 1.13 | 0.71 |
Indian Subcontinent | 0.87 | 0.76 to 1.00 | 0.05 |
Aboriginal | 0.86 | 0.75 to 0.98 | 0.02 |
Unknown | 1.12 | 1.00 to 1.26 | 0.06 |
Other | 0.62 | 0.53 to 0.72 | <0.001 |
Year of first treatment | 1.07 | 1.06 to 1.08 | <0.001 |
The reduced model included the following covariates: facility-level factors (average phosphate), patient case mix (sex, body mass index, race, comorbidities, distance to facility, length of predialysis care, serum phosphate, and hemoglobin), and year. Geographic regions, 14; facilities, 63; patients, 23,902. Median number of patients per facility=795 (interquartile range=532–963). PCKD, polycystic kidney disease.