Figure 1.

Expression of EZH2 in endometrial tissues. (A) EZH2 is overexpressed in the epithelium of endometrial cancer, atypical hyperplasia and complex hyperplasia compared with that in simple hyperplasia and normal endometrium. a, type 1 endometrioid endometrial cancer; b, type 2 endometrial cancer; c, atypical hyperplasia; d, complex hyperplasia; e, simple hyperplasia; f, proliferative endometrium. All images were captured at ×200 magnification using light microscopy and stained with hematoxylin. (B) Expression of EZH2 is higher in the epithelium of endometrial cancer, atypical hyperplasia and complex hyperplasia than in simple hyperplasia and normal endometrium. (C) Expression of EZH2 showed no difference in the stroma among groups. ^*P<0.05 and ^**P<0.01. EZH2, enhancer of zeste homolog 2.