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. 2014 Sep 24;53(19):10370–10377. doi: 10.1021/ic5013796

Figure 1.

Figure 1

Agarose gel electrophoresis of pUC19 with increasing concentrations of (A) 1 and (B) 2 in the dark or irradiated (λ > 400 nm). Lanes 1 and 12, DNA molecular weight standard; lane 2, linear (reaction with EcoR1); lane 3, relaxed circle (reaction with Cu(phen)2); lanes 4–11, 0, 8.25, 16.5, 31.3, 62.5, 125, 250, and 500 μM compound. Cytotoxicity dose response of (C) 1 and (D) 2 in the dark (open squares) or irradiated (closed circles). HL60 cells were incubated for 72 h with compound prior to quantification of viability.