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. 2014 Oct 6;9(10):e107362. doi: 10.1371/journal.pone.0107362

Table 2. Correlation between clinicopathological features and the p-AKT1, p-4E-BP1 expression in gastric cancer specimen.

Clinicopathologicalvariable Number p-AKT1 expression p-4E-BP1 expression
High Low p value High Low p value
Age (years) 0.094 0.518
≥55 46 30 16 29 17
<55 34 21 23 19 15
Gender 0.368 0.054
Male 51 30 21 22 29
Female 29 20 9 19 10
Histological grade 0.001* 0.027*
Well/moderate 36 13 23 14 22
Poorly 44 32 12 28 16
Depth of invasion 0.001* 0.000*
T1/T2 39 18 21 13 26
T3/T4 41 34 7 30 11
Lymph node metastasis 0.000* 0.000*
NO 38 10 28 15 23
YES 42 32 10 33 9
Distant metastasis 0.015* 0.009*
NO 53 22 31 25 28
YES 27 19 8 21 6

The associations between protein expression and clinicopathological variables were estimated using the chi-squared test.

*Significant at the level of p<0.05.