Table 2. Correlation between clinicopathological features and the p-AKT1, p-4E-BP1 expression in gastric cancer specimen.
Clinicopathologicalvariable | Number | p-AKT1 expression | p-4E-BP1 expression | ||||
High | Low | p value | High | Low | p value | ||
Age (years) | 0.094 | 0.518 | |||||
≥55 | 46 | 30 | 16 | 29 | 17 | ||
<55 | 34 | 21 | 23 | 19 | 15 | ||
Gender | 0.368 | 0.054 | |||||
Male | 51 | 30 | 21 | 22 | 29 | ||
Female | 29 | 20 | 9 | 19 | 10 | ||
Histological grade | 0.001* | 0.027* | |||||
Well/moderate | 36 | 13 | 23 | 14 | 22 | ||
Poorly | 44 | 32 | 12 | 28 | 16 | ||
Depth of invasion | 0.001* | 0.000* | |||||
T1/T2 | 39 | 18 | 21 | 13 | 26 | ||
T3/T4 | 41 | 34 | 7 | 30 | 11 | ||
Lymph node metastasis | 0.000* | 0.000* | |||||
NO | 38 | 10 | 28 | 15 | 23 | ||
YES | 42 | 32 | 10 | 33 | 9 | ||
Distant metastasis | 0.015* | 0.009* | |||||
NO | 53 | 22 | 31 | 25 | 28 | ||
YES | 27 | 19 | 8 | 21 | 6 |
The associations between protein expression and clinicopathological variables were estimated using the chi-squared test.
*Significant at the level of p<0.05.