FIG. 7.

Characterization of post-spinal cord injury (SCI) changes observed with very high resolution ultrasound (VHRUS) at the acute (90 min) and subacute (24 h) phases. (A, G) Sagittal VHRUS image. (B, H) Axial VHRUS image. (C, I) Embedded spinal cords during sagittal cryosectioning. (D, J) Embedded spinal cords during axial cryosectioning. (E, F) Histological slices. At 90 min post-SCI, an excellent correlation was found between the VHRUS images, the photographs of the embedded spinal cords, and the histological slices. The acute lesion observed on VHRUS was almost exclusively made up of extravasated red cells (i.e. parenchymal hemorrhage). At 24 h post-SCI, the parenchymal lesion observed with VHRUS is made up of a complex and heterogeneous mix of red blood cells, inflammatory cells, and tissue debris. HE, hematoxylin and eosin.