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. Author manuscript; available in PMC: 2015 Feb 1.

Published in final edited form as: J Neurochem. 2013 Oct 28;128(3):363–375. doi: 10.1111/jnc.12476

Intra-subunit crosslinking: (TM1) and cysteines in TM2 and TM3 of β 2 subunit. A. GABA responses after DTT and Cu⁺⁺:Phen application (1 mM GABA were used). B. GABA responses after DTT and Cu⁺⁺:Phen application (EC₅₀ GABA were used). **p< 0.01, ***p< 0.001 versus Cys-less receptor; two-way ANOVA, and Bonferroni post-tests (n= 5–8). C. The four amino acids are shown, along with the respective Cα-Cα distances, as seen from TM4.

Inline graphic — Intra-subunit crosslinking: (TM1) and cysteines in TM2 and TM3 of β 2 subunit. A. GABA responses after DTT and Cu⁺⁺:Phen application (1 mM GABA were used). B. GABA responses after DTT and Cu⁺⁺:Phen application (EC₅₀ GABA were used). **p< 0.01, ***p< 0.001 versus Cys-less receptor; two-way ANOVA, and Bonferroni post-tests (n= 5–8). C. The four amino acids are shown, along with the respective Cα-Cα distances, as seen from TM4.