Table 5. Improvement in marrow blast count, neutrophil count, and platelet count in patients receiving obatoclax.
Patient | Treatment (phase) | AML Classification | Blast count, % (aspirate) | Neutrophils, ×103/µL | Platelets, ×103/µL | |||
Base-line | End Cycle 2 | Baseline | End Cycle 2 | Baseline | End Cycle 2 | |||
04.002* | 20 mg/d (I) | M4 | 27 | 10 | 9344 | 14,700 | 227 | 206 |
04.003 | 20 mg/d (I) | M3 | 27 | 20 | 3300 | 4400 | 126 | 139 |
05.002 | 20 mg/d (II) | M1 | 33 | 23 | 390 | 360 | 49 | 47 |
*Received eight cycles of obatoclax.
AML, acute myeloid leukemia.