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. 2014 Oct 6;9(10):e108969. doi: 10.1371/journal.pone.0108969

Table 1. Clinical characteristics in 307 cases of febrile neutropenia.

Age, mean years ± SD 40.7±14.2
Female sex 148 (48.2)
Type of cancer
Acute myeloid leukemia 149 (48.5)
Acute lymphoblastic leukemia 45 (14.6)
Chronic myeloid leukemia 18 (5.8)
Multiple myeloma 30 (9.7)
Lymphoma 51 (16.6)
Other solid tumors 14 (4.5)
Relapsing underlying disease 155 (50.4)
Clinical comorbidity 76 (24.7)
Phase of chemotherapy
Induction 76 (24.7)
Consolidation 86 (28.0)
Maintenance 57 (18.6)
HSCT 88 (28.7)
ANC at the time of diagnosis of FN, median cells/mm3 (IQR) 130 (260)
Duration of neutropenia, median days (IQR) 9 (12)
Nosocomial-acquired episodes of FN 250 (81.7)
Bloodstream infection 115 (37.4)
BSI involving Gram-positive bacteria 46 (14.9)
BSI involving Gram-negative bacteria 74 (24.1)
Polymicrobial BSI 12 (3.9)
BSI involving Gram-positive MDR bacteria 27 (8.7)
BSI involving Gram-negative MDR bacteria 12 (3.9)
Proven or probable IFI 22 (7.1)

Data presented as n (%) unless otherwise indicated. SD  =  standard deviation; HSCT  =  hematopoietic stem cell transplantation; ANC  =  absolute neutrophil count; FN  =  febrile neutropenia; IQR  =  interquartile range (P75–P25); BSI  =  bloodstream infection; MDR  =  multi-drug-resistant; IFI  =  invasive fungal infection.