Table 2. A comparison of the occurrence of folds in the Drosophila proteome and interactome.

Fold	Frequency in Drosophila proteome	Frequency in Drosophila interactome	Frequency in Ubx partner list	P-value of enriched fold relative to Drosophila proteome	P-value of enriched fold relative to Drosophila interactome
DNA/RNA binding 3-helical bundle	2.7%	8.4%	17.6%	P<0.05	0.05<P<0.1
α-α superhelix	3.4%	7.2%	14.7%	P<0.05	0.05<P<0.1
Zinc Finger C2H2 and C2HC	3.7%	11.7%	11.8%	P<0.05	0.05<P
dsRBD-like	0.2%	0.9%	5.9%	P<0.05	P<0.05
Protein kinase-like	2.8%	5.6%	5.9%	0.05<P	0.05<P
p-loop containing NTP hydrolases	5.6%	8.4%	8.8%	0.05<P	0.05<P
Ferridoxin-like	2.8%	8.1%	5.9%	0.05<P	0.05<P

p-value of enriched fold relative to Drosophila proteome/interactome was generated using Chi-Squared test.