Table 3. Characteristics and ESR1 XbaI polymorphism genotype distributions in studies included in the meta-analysis.
Author, year | Ethnicity | Quality scorea | Gender (M/F) | Control | Case | P HWE | |||||||||
Control | Case | AA | AG | GG | A | G | AA | AG | GG | A | G | ||||
Wang 2010 [23] | United States(Mixed) | 8 | 0/102 | 0/46 | 48 | 44 | 9 | 140 | 62 | 14 | 24 | 8 | 52 | 40 | 0.81 |
Lu 2009 [28] | China(Asian) | 7 | 0/157 | 0/221 | 112 | 38 | 7 | 262 | 52 | 138 | 73 | 10 | 349 | 93 | 0.12 |
Li 2008 [29] | China(Asian) | 6 | 0/200 | 0/70 | 144 | 46 | 10 | 334 | 66 | 46 | 19 | 5 | 111 | 29 | 0.02 |
Chen 2008 [30] | China(Asian) | 5 | 36/46 | 6/76 | 45 | 29 | 8 | 119 | 45 | 48 | 31 | 3 | 127 | 37 | 0.31 |
Johansson 2005 [31] | Sweden(Caucasian) | 9 | 180/490 | 40/220 | 332 | 281 | 57 | 945 | 395 | 145 | 94 | 21 | 384 | 136 | 0.82 |
Lee 2004 [19] | Korean(Asian) | 7 | 0/268 | 0/137 | 192 | 62 | 14 | 446 | 90 | 89 | 38 | 10 | 216 | 58 | <0.01 |
The quality score was determinded by using the Newcastle-Ottawa quality assessment scale.
ESR1: estrogen receptor 1 gene; M: Male; F: Female; HWE: Hardy-Weinberg equilibrium.