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. 2014 Oct 3;14:196. doi: 10.1186/s12883-014-0196-x

Table 2.

Personal and lifestyle characteristics of included MS patients and controls

MS patients (n = 530) Controls (n = 918) Crude p-value
Tobacco use and exposure
Ever smoker, n (%) 386 (74.5) 495 (54.8) 1.15×10-13a
Ever snuff use, n (%) 60 (11.4) 141 (15.6) 0.029a
Ever exposure to passive smoke, n (%) 380 (72.2) 652 (72.0) 0.94a
Comorbidity
Autoimmune disease other than MS, n (%) 85 (16.0) 151 (16.4) 0.84a
Tonsillectomy, n (%) 118 (23.2) 174 (19.3) 0.078a
Appendectomy, n (%) 60 (11.8) 106 (11.8) 1.0a
Female reproductive health*
Age at menarche, mean (SD) 13.07 (1.38) 12.97 (1.43) 0.28b
Number of children, mean (SD) 1.21 (1.07) 1.77 (1.12) 4.89×10-14b
Age at first child, mean (SD) 27.34 (5.50) 27.05 (4.79) 0.47b

Abbreviation: SD = Standard deviation.

aPearson’s Chi square test.

btwo sided t-test.

*Only women included (ncases = 391, ncontrols = 535).

Missing values are not included in the calculations.