Table 2.
Perioperative characteristics
| Characteristic | High-risk (n=101) | Very high-risk (n=53) | P-value |
|---|---|---|---|
| % Cores positive at biopsy | 33.3 (16.7–50) | 55.8 (30–85.7) | <0.001 |
| Biopsy Gleason sum | 0.258 | ||
| ≤6 | 20 (20) | 10 (19) | |
| 7 | 25 (25) | 11 (21) | |
| ≥8 | 55 (55) | 31 (60) | |
| Pathologic Gleason sum | 0.007 | ||
| ≤6 | 10 (10) | 3 (6) | |
| 7 | 51 (52) | 21 (40) | |
| ≥8 | 38 (38) | 29 (54) | |
| Upgrading | 26 (26) | 14 (26) | 0.904 |
| Downgrading | 33 (32) | 5 (9) | 0.001 |
| Positive surgical margin | 47 (47) | 43 (60) | 0.103 |
| Tumor volume | 4.1 (0.9–4.5) | 5.5 (1.5–8.7) | 0.239 |
| Seminal vesicle invasion | 7 (7) | 12 (23) | 0.005 |
| Lymph node involvement | 7 (7) | 13 (25) | 0.002 |
| Lymph node yield | 15.3 (9–21) | 15.9 (11–21) | 0.663 |
| Lymphovascular invasion | 11 (11) | 7 (13) | 0.656 |
| Perineural invasion | 65 (65) | 34 (65) | 0.962 |
Values are presented as median (interquartile range) and number (%).