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. 2014 Aug 25;35(10):1285–1292. doi: 10.1038/aps.2014.64

Table 1. Laboratory data of mice treated with 24 weeks. Mean±SEM (n=10 per group). bP<0.05 vs LFD group. eP<0.05 vs HFD group.

Variables LFD HFD 100ALA+HFD 200ALA+HFD 300Met+HFD
Primary body weight (g) 23.18±0.23 23.87±0.29 23.81±0.23 23.40±0.29 23.43±0.30
Final body weight (g) 31.00±0.46 50.05±1.01b 41.25±1.63e 37.50±1.43e 35.00±0.53e
Liver weight (g) 1.06±0.04 1.91±0.18b 1.42±0.21e 1.25±0.05e 1.33±0.05e
BMI (g/cm2) 0.32±0.07 0.58±0.10b 0.41±0.13e 0.37±0.09e 0.39±0.11e
Abdominal circumference (cm) 7.63±0.13 9.83±0.08b 8.43±0.37 7.98±0.14e 7.50±0.14e
Water intake (mL/d) 6.97±0.16 7.87±0.17b 6.87±0.19 6.26±0.05e 6.52±0.14e

LFD, low-fat diet, negative control group; HFD, high fat diet; 100ALA+HFD, high fat diet plus (100 mg/kg) alpha-lipoic acid; 200ALA+HFD, high fat diet plus (200 mg/kg) alpha-lipoic acid; 300Met+HFD, high fat diet plus (300 mg/kg) metformin, positive control group.