Figure 5.

Influence of enalapril on the expression of NLRP3, caspase-1, IL-1β, and IL-18 by Western blot. Rats were given overload BSA with or without enalapril, and expression of NLRP3, caspase-1, IL-1β, and IL-18 proteins were measured by Western blot (A). Semiquantitative analysis using Image J software. In the BSA-overload group, NLRP3, caspase-1, IL-1β, and IL-18 protein were significantly elevated, as were pro-caspase-1, pro-IL-1β, and pro-IL-18; and enalapril treatment decreased their expression (B). Data are represented as mean±SD. n=3. ^bP<0.05 vs control group. ^eP<0.05 vs enalapril group.