Table 2. Average body weights were quantified when tumors were excised from allografted C57BL/6 mice on d 10 after 7 d of treatment with increasing doses of S115.
Group | Colon26-BALB/c mouse model Body weight (g) |
B16-C57BL/6 mouse model Body weight (g) |
||
---|---|---|---|---|
D 0 | D 10 | D 0 | D 10 | |
Saline (20 mL/kg) | 17.62±0.39 | 21.84±0.64 | 17.78±0.37 | 22.05±1.14 |
S115 (2 mg/kg) | 17.75±0.43 | 21.49±0.76 | 17.82±0.69 | 21.84±0.87 |
S115 (8 mg/kg) | 17.83±0.35 | 20.29±0.60 | 18.15±0.29 | 21.22±1.05 |
S115 (32 mg/kg) | 17.91±0.18 | 20.20±1.79 | 17.75±0.38 | 21.33±1.00 |