Table 4.
Group differences in FA in AFQ-identified fiber tracts
| AFQ fiber group |
CTL FA |
MDD FA |
p value | ||
|---|---|---|---|---|---|
| M | SD | M | SD | ||
| Left corticospinal tract |
0.620 |
0.020 |
0.644 |
0.020 |
<0.002 |
| Right corticospinal tract | 0.614 | 0.021 | 0.639 | 0.015 | <0.001 |
p values were computed using two-sample t-tests and a false discovery rate (FDR) procedure was used to account for false positives as a result of multiple comparisons. See Figure 1 for corticospinal tract (CST) renderings and graphical display of differences.
AFQ automated fiber quantification, MDD major depressive disorder, CTL control, FA fractional anisotropy, M mean, SD standard deviation.