Table 2.
Guest |
S0 (mg/L) |
CD | Kf (M−1) | St/S0a | CE | Molar ratio (PP:CD) | Increase in formulation bulk |
trans-Anethole (1) | 22 | α-CD | 1274 | 11 | 0.19 | 1:6.38 | 42 |
β-CD | 537 | 3 | 0.08 | 1:13.75 | 106 | ||
HP-β-CD | 1510 | 14 | 0.22 | 1:5.54 | 56 | ||
RAMEB | 2157 | 17 | 0.31 | 1:4.18 | 38 | ||
CRYSMEB | 1782 | 15 | 0.26 | 1:4.84 | 40 | ||
Estragole (2) | 48 | α-CD | 682 | 4 | 0.22 | 1:5.54 | 36 |
β-CD | 882 | 3 | 0.28 | 1:4.51 | 35 | ||
HP-β-CD | 1412 | 11 | 0.46 | 1:3.19 | 32 | ||
RAMEB | 1694 | 12 | 0.55 | 1:2.83 | 26 | ||
CRYSMEB | 1512 | 10 | 0.49 | 1:3.05 | 25 | ||
Isoeugenol (3) | 665 | α-CD | 110 | 2 | 0.45 | 1:3.24 | 19 |
β-CD | 210 | 1.5 | 0.85 | 1:2.18 | 15 | ||
HP-β-CD | 449 | 2.7 | 1.82 | 1:1.55 | 14 | ||
RAMEB | 428 | 2.6 | 1.73 | 1:1.58 | 13 | ||
CRYSMEB | 312 | 2.5 | 1.26 | 1:1.79 | 13 | ||
Eugenol (4) | 1038 | α-CD | 246 | 2 | 1.56 | 1:1.64 | 10 |
β-CD | 513 | 2.1 | 3.25 | 1:1.31 | 9 | ||
HP-β-CD | 445 | 2.2 | 2.81 | 1:1.36 | 12 | ||
RAMEB | 550 | 2.2 | 3.48 | 1:1.29 | 11 | ||
CRYSMEB | 440 | 2.1 | 2.78 | 1:1.36 | 10 | ||
p-Coumaric acid (5) | 344 | α-CD | 1988 | 4.8 | 4.17 | 1:1.24 | 7 |
β-CD | 306 | 2.8 | 0.64 | 1:2.56 | 18 | ||
HP-β-CD | 1099 | 4.4 | 2.30 | 1:1.43 | 13 | ||
RAMEB | 1228 | 4.4 | 2.57 | 1:1.39 | 11 | ||
CRYSMEB | 900 | 4 | 1.89 | 1:1.53 | 11 | ||
Caffeic acid (6) | 300 | α-CD | 1819 | 5.5 | 3.03 | 1:1.33 | 7 |
β-CD | 425 | 3.5 | 0.71 | 1:2.41 | 15 | ||
HP-β-CD | 534 | 3.8 | 0.89 | 1:2.12 | 18 | ||
RAMEB | 825 | 4.4 | 1.37 | 1:1.73 | 13 | ||
CRYSMEB | 552 | 3.8 | 0.92 | 1:2.09 | 14 | ||
Ferulic acid (7) | 333 | α-CD | 1737 | 5.2 | 2.98 | 1:1.34 | 7 |
β-CD | 326 | 3.1 | 0.56 | 1:2.79 | 16 | ||
HP-β-CD | 833 | 4.4 | 1.43 | 1:1.70 | 13 | ||
RAMEB | 1045 | 4.8 | 1.79 | 1:1.56 | 11 | ||
CRYSMEB | 512 | 3.8 | 0.88 | 1:2.14 | 13 |
aSt and S0 are the guest solubility in 10 mM CD solution and in water, respectively.