Table 2.
Laboratory values
| Lab value | Car2+/+ Mice | Car2−/− Mice | P Value |
|---|---|---|---|
| Urine laboratory tests | |||
| pH | 5.73 ± 0.11 | 6.38 ± 0.34 | 0.013* |
| Serum chemistries | |||
| pH | 7.30 ± 0.07 | 7.12 ± 0.03 | <0.001* |
| HCO3−, mmol/l | 19.93 ± 2.61 | 17.24 ± 1.43 | 0.007* |
| K+, mmol/l | 6.32 ± 1.01 | 4.90 ± 1.47 | 0.017* |
| Complete blood counts and differentials | |||
| White blood cells, K/μl | 9.13 ± 0.84 | 8.69 ± 1.06 | 0.754 |
| Neutrophils, K/μl | 1.08 ± 0.10 | 0.96 ± 0.07 | 0.356 |
| Lymphocytes, K/μl | 7.43 ± 0.74 | 7.21 ± 0.94 | 0.861 |
| Monocytes, K/μl | 0.61 ± 0.08 | 0.49 ± 0.07 | 0.292 |
| Eosinophils, K/μl | 0.01 ± 0.00 | 0.02 ± 0.01 | 0.347 |
| Hematocrit, % | 44.93 ± 1.12 | 44.17 ± 1.90 | 0.579 |
Values are means ± SD. For urine laboratory tests, n = 3 Car2+/+ mice and 7 Car2−/− mice except for serum chemistries, where n = 11 mice/genotype; for complete blood counts and differentials, n = 3 mice/genotype.
*
Statistically significant difference.