Table 3.
RT2 bacterial response array results
| Gene Name | Gene Symbol | Functional Gene Grouping | Fold Change | P Value |
|---|---|---|---|---|
| Expression in Car2−/−mice relative to Car2+/+ mice | ||||
| Lipocalin 2 | Lcn2 | Antimicrobial peptide | +4.05 | 0.03 |
| Cathelicidin antimicrobial peptide | Camp | Antimicrobial peptide | +2.03 | 0.04 |
| Expression in infected Car2−/− mice relative to infected Car2+/+ mice | ||||
| C-reactive protein, pentraxin-related | Crp | Bacterial pattern recognition receptors and the inflammatory response | −3.9 | 0.045 |
| Expression in infected Car2+/+mice relative to Car2+/+ mice | ||||
| Lipocalin 2 | Lcn2 | Antimicrobial peptide | +4.5 | 0.04 |
| CD14 antigen | Cd14 | Inflammatory response | +4.5 | 0.04 |
| Tumor necrosis factor | Tnf | Inflammatory response | +4.4 | 0.04 |
| Mediterranean fever | Mefv | Inflammatory response | +20.9 | 0.03 |
| Expression in infected Car2−/−mice relative to Car2−/− mice | ||||
| Interferon regulatory factor 5 | Irf5 | Cytokines and chemokines | −3.5 | 0.04 |
| NLR family, CARD domain containing 4 | Nlrc4 | Inflammasomes and the inflammatory Response | −3.5 | 0.03 |
| C-reactive protein, pentraxin-related | Crp | Bacterial pattern recognition receptors and the inflammatory response | −3.5 | 0.01 |