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Effect of PD-0325901 on ERK, mTOR, JNK, and STAT signaling pathways following 2 h TI treatment. Western blots of pERK (A), pS6 (B), p-c-Jun (C), and pSTAT3 (D) in mice. Values are represented as fold increase of control mice. All results shown are means ± SE of n = 6–10 mice. **P < 0.01.
