Fig. 4.
Effect of PD-0325901 on the expression of early response genes following 2 h TI treatment. qRT-PCR analysis of c-Fos (A), Egr-1 (B), c-Jun (C), JunB (D), and Ier3 (E) in mouse pancreas. F: GAPDH was included as a control. Values are represented as fold increase of control mice. All results shown are means ± SE of n = 8–10 mice. *P < 0.05.