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Measurement of renal function. Twenty-four-hour urine collection from WT and 3M was obtained from mice individually housed in metabolic cages. Urinary volume, albumin, and creatinine levels were determined. A: urinary volume. B: albumin-to-creatinine ratio. C: albumin excretion. Values are expressed as means ± SE; n = 3–6. *P < 0.05 and +P ≤ 0.07 vs. respective control mice.
