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. Author manuscript; available in PMC: 2014 Nov 1.
Published in final edited form as: Stroke. 2013 Sep 10;44(11):3097–3102. doi: 10.1161/STROKEAHA.113.002752

Table 2.

Potential predictors of in-hospital mortality and three months' outcome

Comparison of patients survived vs deceased at discharge Comparison of patients with good vs poor outcomes
Survived (n=103) Deceased (n= 28) p-value Good outcome (mRS<3) (n= 53) Poor outcome (mRS≥3) (n= 78) p-value
Age (mean +/− sd), y 70 +/− 16 77 +/− 16 p = 0.05 * 70 +/− 16 72 +/− 16 p = 0.45 *
59% Male 64% Male 64% Male 58% Male
Sex 41% Female 36% Female p = 0.63 ** 36% Female 42% Female p = 0.46 **
History of Hypertension 68/103 (66%) 22/28 (79%) p = 0.20 ** 33/53 (62%) 57/78 (73%) p = 0.15 **
SBP at admission, mmHg 165 +/− 38 180 +/− 46 p = 0.09 * 156+/− 38 176+/− 40 p = 0.01 *
DBP at admission, mmHg 84 +/− 23 92 +/− 32 p = 0.13 * 80 +/− 21 90 +/− 28 p = 0.03 *
Glucose (mean +/− sd), mg/dL 145 +/− 56 139 +/− 39 p = 0.59 * 138 +/− 47 147 +/− 57 p = 0.30 *
Platelets (mean +/− sd) 245 +/− 69 252 +/− 103 p = 0.65 * 238 +/− 68 252 +/− 83 p = 0.30 *
Anticoagulation 14/103 (14%) 8/28 (29%) p = 0.09 ** 7/53 (13%) 15/78 (19%) p = 0.65 **
Antiplatelet Medication 34/103 (33%) 12/28 (43%) p = 0.33 ** 19/53 (36%) 27/78 (35%) p = 0.89 **
INR (mean +/− sd) 1.2 +/− 0.5 1.6 +/− 0.8 p = 0.05 * 1.2 +/− 0.4 1.3 +/− 0.7 p = 0.11 *
Vitamin K 12/103 (12%) 7/28 (25%) p = 0.13 + 5/53 (9%) 14/78 (18%) p = 0.21 +
Platelet transfusion 8/103 (8%) 4/28 (14%) p = 0.28 + 3/53 (6%) 9/78 (12%) p = 0.36 +
Fresh Frozen Plasma 11/103 (11%) 6/28 (21%) p = 0.20 + 7/53 (13%) 10/78 (13%) p = 1.00 +
Admission ICH Volume (mean +/− sd), mL 20.0 +/− 20.7 48.6 +/− 39.1 p = 0.001 * 15.3 +/− 14.3 33.5 +/− 32.6 p < 0.0001 *
Follow-up ICH Volume (mean +/− sd), mL 20.5 +/− 21.1 61.6 +/− 48.9 p < 0.0001 * 15.1 +/− 14.3 38.9 +/− 39.3 p < 0.0001 *
Presence of IVH 29/103 (28%) 19/28 (68%) p < 0.0001 ** 8/53 (15%) 40/78 (51%) p < 0.0001 **
Time of admission to first CT (mean +/− sd), h 2.4 +/− 3.0 0.9 +/− 0.6 p<0.0001 * 2.7 +/− 3.2 1.7 +/− 2.4 P=0.02 *
Time of first CTto follow up CT (mean +/− sd), h 14.7 +/− 8.7 11.7 +/− 8.6 p = 0.12 * 14.1 +/− 7.3 14.0 +/− 9.7 p = 0.97 *
Admission ICH Volume (median), mL 12.7 38.5 p < 0.0001 ++ 9.5 18.6 p < 0.0001 ++
Followup ICH volume (median), mL 13.0 64.9 p < 0.0001 ++ 10.5 18.7 p < 0.0001 ++
Spot sign presence 12/103 (12%) 19/28 (68%) P< 0.0001 ** 3/53 (6%) 28/78 (36 %) P= 0.0002 **
SS Score
0 91 9 P = <.0001 ** 50 50 P = 0.1483 **
1 7 7 P = 0.0057 ** 2 12 P = 0.0347 **
2 4 7 P = 0.0004 ** 1 10 P = 0.0269 **
3 1 3 P = 0.0079 ** 0 4 P = 0.0943 **
4 0 2 P = 0.0063 ** 0 2 P = 0.2401 **
Average rate of ICH expansion (mean +/− sd), mL/h 0.03 +/− 0.39 2.81 +/− 5.55 p = 0.01 * −0.04 +/− 0.33 1.07 +/− 3.55 p = 0.01 *

Key:

*

Student's t-test

**

Chi- Square Test

+

Fisher Exact Test

++

Mann Whitney Test