Table 4.

Canonical pathways represented by the genes altered in hypoxic carotid arteries

Canonical Pathways	−Log(P Value)	Ratio	Molecules
Aryl hydrocarbon receptor signaling	2.27E +00	2.48E-02	MYC, ALDH1A1, NQO2, ESR1
Factors promoting cardiogenesis in vertebrates	2.01E +00	3.19E-02	BMP4, PRKCD, ACVR1
Acute phase response signaling	1.98E +00	2.23E-02	IL6ST, IL18, APOA1, SOCS2
Embryonic stem cell pluripotency	1.91E +00	3.03E-02	IL6ST, MYC, BMP4
ERK/MAPK Signaling	1.17E +00	1.46E-02	MYC, PRKCD, ESR1