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The crystal structure of a putative glycosyltransferase from the archaeal virus, STIV. STIV A197 (PDB ID 2C0N [39]) adopts the glycosyltransferase GT-A family fold and contains many of the conserved catalytic residues seen throughout the family, including the DXD motif (located in a loop, colored magenta), a catalytic base, (Asp151, located in a helix, colored magenta), and a conserved manganese binding site (not depicted).
