TABLE 3.
Effects of Fragile X Based on Estimated Trajectories of Vineland Scores Using Mixed Effects Modeling
| Males With Fragile X Versus Control Males | Females With Fragile X Versus Control Females | Group (Fragile X or Control) by Gender Interaction | ||||
|---|---|---|---|---|---|---|
| Difference in Standard Scores | P | Difference in Standard Scores | P | Difference in Standard Scores | P | |
| Adaptive behavior composite | ||||||
| At age 2 | −31.932 | <.001* | −35.909 | <.001* | −9.118 | .106 |
| At age 6 | −45.027 | <.001* | −29.708 | <.001* | −23.867 | <.001* |
| At age 10 | −53.575 | <.001* | −27.596 | <.001* | −29.980 | <.001* |
| At age 14 | −57.576 | <.001* | −29.574 | <.001* | −27.457 | <.001* |
| At age 18 | −57.031 | <.001* | ||||
| Socialization | ||||||
| At age 2 | −23.345 | <.001* | −21.261 | <.001* | −13.768 | <.001* |
| At age 6 | −35.029 | <.001* | −22.982 | <.001* | −20.811 | <.001* |
| At age 10 | −43.793 | <.001* | −24.635 | <.001* | −25.002 | <.001* |
| At age 14 | −49.637 | <.001* | −26.220 | <.001* | −26.340 | <.001* |
| At age 18 | −52.560 | <.001* | ||||
| Communication | ||||||
| At age 2 | −33.429 | <.001* | −27.748 | <.001* | −18.845 | <.001* |
| At age 6 | −46.593 | <.001* | −27.355 | <.001* | −28.073 | <.001* |
| At age 10 | −55.428 | <.001* | −28.420 | <.001* | −31.517 | <.001* |
| At age 14 | −59.936 | <.001* | −30.942 | <.001* | −29.174 | <.001* |
| At age 18 | −60.116 | <.001* | ||||
| Daily Living | ||||||
| At age 2 | −23.040 | <.001* | −34.537 | <.001* | −7.041 | .157 |
| At age 6 | −41.578 | <.001* | −24.962 | <.001* | −27.697 | <.001* |
| At age 10 | −52.660 | <.001* | −20.680 | <.001* | −35.603 | <.001* |
| At age 14 | −56.284 | <.001* | −21.692 | <.001* | −30.759 | <.001* |
| At age 18 | −52.450 | <.001* | ||||
P < .0001.