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A: percentage of cardiac rupture deaths in C57BL/6 mice during the first week after myocardial infarction (MI). Thymosin-β4 (Tβ4) significantly reduced the incidence of cardiac rupture induced by MI. Values in parentheses are numbers of mice in the sham-operated (sham), MI + vehicle, and MI + Tβ4 groups. B: Tβ4 contents in mouse hearts, showing doubled cardiac Tβ4 in the Tβ4-treated group compared with nontreated groups. *P < 0.005; †P < 0.05; ‡P < 0.005.
