Table 2.
Patient Group | Delay to PCI (Minutes) | Sample Size | Unadjusted Event Rate (%) | Unadjusted Hazard Ratio (95% CI) | Adjusted Hazard Ratio (95% CI) |
---|---|---|---|---|---|
FMC‐to‐PCI, entire cohort | Time as a continuous variable 0 to 360 minutes | 13 790 | 8.6 | 1.06 (1.03 to 1.09)* | 1.06 (1.04 to 1.09)* |
0 to 30 | 2237 | 7.0 | 1.00 | 1.00 | |
31 to 60 | 3557 | 7.2 | 1.02 (0.84 to 1.25) | 1.08 (0.88 to 1.33) | |
61 to 90 | 3238 | 9 | 1.29 (1.06 to 1.56) | 1.26 (1.03 to 1.55) | |
91 to 120 | 1934 | 9.9 | 1.43 (1.16 to 1.77) | 1.41 (1.14 to 1.76) | |
121 to 360 | 2824 | 10.4 | 1.51 (1.24 to 1.83) | 1.51 (1.23 to 1.86) | |
FMC‐to‐PCI, patients with a pre‐hospital ECG | Time as a continuous variable 0 to 360 minutes | 7053 | 8.6 | 1.08 (1.04 to 1.13)* | 1.05 (1.01 to 1.10)* |
0 to 30 | 520 | 5 | 1.00 | 1.00 | |
31 to 60 | 2379 | 7.1 | 1.42 (0.94 to 2.15) | 1.34 (0.88 to 2.05) | |
61 to 90 | 2042 | 9.5 | 1.94 (1.29 to 2.92) | 1.57 (1.03 to 2.41) | |
91 to 120 | 1015 | 10.2 | 2.10 (1.37 to 3.23) | 1.61 (1.03 to 2.53) | |
121 to 360 | 1097 | 10.4 | 2.18 (1.42 to 3.33) | 1.71 (1.10 to 2.67) | |
Symptom‐to‐PCI, entire cohort | Time as a continuous variable 0 to 480 minutes | 11 489 | 8.3 | 1.06 (1.02 to 1.10)* | 1.05 (1.01 to 1.09)* |
0 to 60 | 332 | 5.7 | 1.00 | 1.00 | |
61 to 120 | 2567 | 7.2 | 1.26 (0.79 to 2.02) | 1.50 (0.93 to 2.43) | |
121 to 180 | 3146 | 8.2 | 1.45 (0.91 to 2.31) | 1.47 (0.92 to 2.35) | |
181 to 240 | 2142 | 8.5 | 1.51 (0.94 to 2.42) | 1.45 (0.90 to 2.35) | |
241 to 480 | 3302 | 9.2 | 1.63 (1.03 to 2.60) | 1.68 (1.05 to 2.69) |
FMC indicates first medical contact; PCI, percutaneous coronary intervention.
Hazard ratios expressed as mortality/30 minutes of time delay.
Hazard ratios expressed as mortality/60 minutes of time delay.