Table 2.
Baseline Characteristics According to the Level of FAC
| Variable | FAC <80% (n=2763) | FAC >80% (n=3760) | P Value |
|---|---|---|---|
| Demographics/baseline characters | |||
| Age | 49.9 (40.6, 60.7) | 49.0 (41.8, 57.3) | 0.006 |
| Males | 1518 (55%) | 2276 (61%) | <0.001 |
| Ethnicity | 0.002 | ||
| Caucasian | 2274 (82%) | 2979 (79%) | |
| Others/not reported | 489 (18%) | 781 (21%) | |
| Body mass index (kg/m2) | 30.4 (26.7, 35.5) | 26.7 (24.3, 29.9) | <0.001 |
| Waist/Hip ratio | 0.9 (0.8, 1.0) | 0.9 (0.8, 0.9) | <0.001 |
| Smoking | <0.001 | ||
| Never | 1256 (46%) | 2175 (58%) | |
| Past | 965 (35%) | 1167 (31%) | |
| Current | 539 (20%) | 415 (11%) | |
| Family history of coronary disease | 1448 (52%) | 2091 (56%) | 0.010 |
| Diabetes | 401 (15%) | 205 (5%) | <0.001 |
| Medications | |||
| Lipid lowering therapy | 178 (6%) | 210 (6%) | 0.148 |
| Hypertension therapy | 846 (31%) | 711 (19%) | <0.001 |
| Resting BP | |||
| Resting diastolic BP | 80.0 (72.0, 88.0) | 80.0 (72.0, 88.0) | 0.303 |
| Resting systolic BP | 126.0 (114.0, 140.0) | 126.0 (114.0, 140.0) | 0.910 |
| Fasting blood tests, mg/dL | |||
| Total cholesterol | 210.0 (183.0, 239.0) | 208.0 (183.0, 238.0) | 0.266 |
| HDL‐cholesterol | 44.0 (37.0, 53.0) | 48.0 (40.0, 58.0) | <0.001 |
| LDL‐cholesterol | 127.0 (104.0, 153.0) | 130.0 (106.0, 154.0) | 0.107 |
| Glucose | 99.0 (92.0, 112.0) | 95.0 (89.0, 102.0) | <0.001 |
| Triglycerides | 159.5 (114.0, 227.0) | 129.0 (92.0, 188.0) | <0.001 |
| Exercise test parameters | |||
| Abnormal heart rate recovery at 1 minute (<12/min) | 999 (36%) | 612 (16%) | <0.001 |
| Chronotrophic incompetence | 1136 (41%) | 434 (12%) | <0.001 |
| Premature ventricular beats | <0.001 | ||
| None | 1973 (71%) | 2527 (67%) | |
| ≤5 /minute | 576 (21%) | 948 (25%) | |
| >5 /minute | 214 (8%) | 285 (8%) | |
| Positive ST changes | 184 (7%) | 247 (7%) | 0.885 |
| Blood pressure response | <0.001 | ||
| Normal | 2404 (87%) | 3460 (92%) | |
| Hypotensive | 57 (2%) | 61 (2%) | |
| Hypertensive | 302 (11%) | 239 (6%) | |
| Chest pain | <0.001 | ||
| Absent | 2508 (91%) | 3529 (94%) | |
| Atypical chest pain | 145 (5%) | 180 (5%) | |
| Typical angina | 110 (4%) | 51 (1%) |
BP indicates blood pressure; FAC, functional aerobic capacity; HDL, high‐density lipoprotein; LDL, low‐density lipoprotein.