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. 2014 Apr 25;3(2):e000874. doi: 10.1161/JAHA.114.000874

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© 2014 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley Blackwell.

This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

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Figure 1. — Maraviroc (MVC) therapy preserves diastolic function in SIV‐infected macaques. A, MVC‐treated SIV‐infected macaques had preserved mitral inflow E wave deceleration times (MV DT). B, The median MV isovolumetric relaxation time (IVRT) was also significantly lower with MVC treatment vs untreated SIV‐infected macaques. MVC also prevented increases in tissue Doppler (TDI)‐derived lateral myocardial relaxation time (myoRT, C) and septal myoRt (D) as compared to untreated SIV‐infected macaques. Analyses represent Mann–Whitney tests; bars represent median values. SIV indicates simian immunodeficiency virus.