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. 2014 Jul 4;2(7):e12053. doi: 10.14814/phy2.12053

Figure 1.

Figure 1.

C57BL/6 ksr2−/− mice are small and lean at weaning, but become obese as adults. (A) Body weights of WT and ksr2−/− mice compared at 2.5 (n = 8–9), 5 (n = 3–5), and 7 (n = 3–5 per genotype) weeks of age. Body weights (B) and percentage body fat (C) determined by DEXA of WT and ksr2−/− mice compared from 2.5 to 24 weeks of age. 2.5 weeks, n = 8–9; 5–7 weeks, n = 3–5; 9–14 weeks, n = 4–9; and 17–24 weeks, n = 2–4 per genotype. (D) Lean and fat mass determined by DEXA of WT and ksr2−/− mice at 5–7 weeks of age (n = 8) and 12–14 weeks of age (n = 8–11 per genotype). (E) The weight of adipose distinct depots was determined in WT and ksr2−/− mice. SQ, subcutaneous; IFP, inguinal fat pad; RP, retroperitoneal; BAT, brown adipose tissue. *P < 0.05, **P < 0.01, ***P < 0.001, and ****P < 0.0001.