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. 2014 Jul 4;2(7):e12064. doi: 10.14814/phy2.12064

Figure 3.

Figure 3.

Runners consumed more calories compared to sedentary mice over 4 weeks on a high‐fat diet. (A) The mean total caloric intake (kcal) for wild‐type (WT) and IL‐6 knockout (KO) groups with (RUN) and without (SED) voluntary access to running wheels fed a high‐fat diet for 4 weeks. (B) The mean cumulative caloric intake (kcal) for WT and KO groups (RUN & SED) over 4 weeks on a high‐fat diet. aDenotes significant differences (P ≤ 0.05) between RUN and SED mice. bDenotes significant differences (P ≤ 0.05) between KO RUN and both KO SED and WT SED groups. cDenotes significant differences (P ≤ 0.05) between WT RUN and both KO SED and WT SED groups. Data are presented as mean ± SEM, (n = 6–8 per group).