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Lack of IL‐6 disrupts the relationship between caloric intake and weight gain in runners. The correlation between total caloric intake (kcal) and total change in body weight (grams) in wild‐type (WT) (n = 5) and IL‐6 knockout (KO) (n = 8) groups with (RUN) voluntary access to running wheels fed a high‐fat diet for 4 weeks. The data from one WT animal were removed as an outlier based on the value being greater than two standard deviations from the mean.
