Table 1.
Genes whose expression was induced in Siglec‐14+ THP‐1 human monoblastoid cell line by NTHi stimulation.
| Gene symbol | Protein product (synonym) | Fold induction1 | Criteria (3a)2 | Criteria (3b)2 |
|---|---|---|---|---|
| TNFAIP6 | Tumor necrosis factor‐inducible gene 6 protein (TSG‐6) | 11.0 | No | Yes |
| LOC285628 | – | 10.1 | No | Yes |
| CCL20 | C‐C motif chemokine 20 (LARC, MIP‐3 α) | 4.3 | Yes | Yes |
| IL1B | Interleukin‐1 β | 3.8 | Yes | Yes |
| RRAD | GTP‐binding protein RAD | 3.8 | Yes | Yes |
| CXCL1 | Growth‐regulated α protein (GRO‐α) | 3.8 | Yes | No |
| EBI3 | Interleukin‐27 subunit β (EBV‐induced gene 3 protein) | 3.6 | Yes | Yes |
| BIRC3 | Baculoviral IAP repeat‐containing protein 3 (RING finger protein 49) | 3.5 | No | Yes |
| ICAM1 | Intercellular adhesion molecule 1 (CD54) | 3.5 | Yes | Yes |
| CCL2 | C‐C motif chemokine 2 (MCP‐1) | 3.4 | Yes | Yes |
| TNFRSF9 | Tumor necrosis factor receptor superfamily member 9 (CD137, 4‐1BB) | 3.3 | Yes | Yes |
| IL8 | Interleukin‐8 (CXCL8) | 3.3 | Yes | Yes |
1
The ratio of signal intensity in Siglec‐14/THP‐1 cells stimulated with NTHi as compared with that without stimulation.
2
See Materials and Methods section for details.