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Effects of peptides on binding of yeast to BSA-coated surfaces. Micrographs and cell counts of channel surfaces with cells expressing Als5p or Als5pV326N sheared at 0.8 dynes/cm2 for 2 h. Micrographs are representative field enlargements of the channel surface. Scale bar, 5 μm. (A) Cells were sheared in the absence or presence of anti-amyloid V326N peptide or a scrambled peptide of the same composition (200 μg/ml). (B) Channels after an additional 10 min of high shear at 20 dyne/cm2.
