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. 2014 Oct;27(4):647–664. doi: 10.1128/CMR.00002-14

TABLE 5.

Contemporary studies of invasive disease and/or bloodstream infection due to Streptococcus pneumoniae in nonselected populations

First author (reference) Population, yr Annual invasive disease incidence per 100,000 BSI rate or proportion (%) of isolates in blood
Rudnick (108) Toronto, Canada, 1995–2011 9 Not reported
Feemster (109) Philadelphia, PA, 2005–2008 Not reported 12.3 per 100,000
Helferty (110) Northern Canada, 1999–2010 25.8 Not reported
Ingels (111) Denmark, 2000–2010 17.7 (2008–2010) Not reported
Rosen (112) Eight U.S. regions, 1998–2009 13.5 (overall; range of 11.2 to 18 between regions during 2009) Not reported
Harboe (113) Denmark, 1938–2007 Approximately 20 (1998–2007) 81
Weatherholtz (114) Navajo Nation, USA, 1995–2006 51 (2004–2006) Not reported
Motlova (115) Czech Republic, 2000–2006 2.3–4.3 Not reported
Hsieh (116) Taiwan, 2007 2.6 ≥94
Kellner (117) Calgary, Canada, 1998–2007 11.2 (2003–2007) 89
Baggett (118) Two areas in rural Thailand, 2005–2007 Not reported 3.7 per 100,000 (Sa Kaeo Province) and 7.6 per 100,000 (Nakhon Phanom Province)
Bruce (119) Seven circumpolar regions, 1999–2005 21.6 for Canada (2003–2005), 19.8 for Greenland (2000–2005), 16.2 for Norway (2000–2005), 15.8 for Alaska (2001–2005), 14.6 for Iceland (2000–2005), 11.6 for Finland (2000–2005), 9.1 for Sweden (2003–2005) Not reported
Heffernan (120) New Zealand, 1998–2005 12.4 93
Lacapa (121) Fort Apache Indian Reserve, USA, 1991–2006 87 (2001–2006) Not reported
Klemets (122) Finland, 1995–2002 10.6 9.9 per 100,000
Einarsdottir (123) Iceland, 1975–2004 16.7 (1990–2004) Not reported
Stephens (124) Atlanta, GA, 1994–2002 18 (2000–2002) 95
Andresen (125) Canberra, Australia, 1998–2000 15.2 Not reported