FIG 3.

Correlations between genome sizes of prokaryotes and some genomic and phenotypic features. (A) Correlation coefficients for annotation data and doubling times. (Data for eukaryote-like kinases are from reference 183, data for doubling times are from reference 184, and the remaining data are from the IMG database [180].) All P values were <0.001, with the exception of the correlations for doubling times (nonsignificant P values). (B) Pearson's correlation between the number of reactions and the number of ORFs for 49 manually curated metabolic network reconstructions (P value of 0.001637) (for the full list and references, see Data Set S1 in the supplemental material). The blue square represents a theoretical minimal metabolic network (46).