TABLE 3.

Comparison of relevant characteristics of Escherichia coli and Mycoplasma genitalium

Parameter	Value for species
	Escherichia coli	Mycoplasma genitalium
Characteristics of species
No. of ORFs	4,325a	482b
No. of NCBI COGs	2,131	362
No. of NCBI structure direct links	1,096	6
DNA content (mg/ml cell vol)c	13	100
Doubling time (h)d	0.35	12
Species knowledge indexe	47.5	1.53
Characteristics of in silico metabolic network reconstruction
Model ID	iJO1366a	iPS189b
No. of genes	1,366	189
Overall accuracy of gene essentiality predictions (%)	91	87
No. of reactions	2,251	262
Metabolic	1,473	178
Transport	778	84
No. of unique metabolites	1,136	274
No. of gene-associated reactions	1,310	168
No. of spontaneous reactions	25	6
No. of non-gene-associated reactions	133	88

^aSee reference 187.

^bSee reference 72.

^cSee reference 139.

^dSee reference 184.

^eSee reference 112.