FIG 2.
Genetic organizations of the genomic regions of SfII, S. flexneri, and E. coli strains carrying the oacD gene. Sequences of serotype-converting phage SfII, S. flexneri strains Sf301, 2457T, 2747-71, HN006, and K-1770, and E. coli strains KTE33 and 1-176-05_S3_C2 were obtained from the NCBI database. Genomic sequences of serotype 3a strains 51575 and G1665 were obtained by PCR amplification. The open reading frames (ORFs) were annotated as submitted in NCBI or predicted using ORF Finder and are shown as thick arrows. The locus tags are shown within arrows, and the encoding proteins are listed above. The conserved genes are shown in different colors: proA and adrA, dark blue; gtr locus, pink; ISsf13, green; oacD, red; tail fiber light blue. The conserved oacD-carrying prophage genome and oacB-carrying transposon are highlighted in red and gray, respectively. The defective gtrII gene in strain HN006 is marked with a blue star.