FIG 2.

Alignment of unique sequences of the TP0136 and TP0548 loci of clinical isolates collected in the Czech Republic between 2004 and 2013 (5; this study). Only positions showing nucleotide differences (indels, substitutions) are shown. Coordinates correspond to TP0136 and TP0548 in the T. pallidum subsp. pallidum (TPA) SS14 genome (accession no. CP004011) (37). Nucleotide differences shown on a gray background indicate differences between the SS14-like and Nichols-like groups of strains. Nucleotide changes shown on black and white backgrounds represent unique differences found in clinical isolates.