TABLE 4.
Comparison of features between two commercial multiplex platforms for the detection of gastrointestinal pathogens
| Feature | FilmArray | Luminex |
|---|---|---|
| Maximum no. of targets | 23 | 15 |
| Processing time per run (min) | 2 | 45 |
| Separate extraction required (min) | No | Yes (∼45) |
| Time/run (h) | ∼1 | ∼3.5 |
| Throughput (no. specimens/run) | 1 | 96 |
| Technology | Nested PCR plus melting curve | PCR plus xTag (fluorescent bead-based detection) |
| Regulatory status | FDA cleared (22 targets) | FDA cleared (11 targets); RUOa (4 additional targets) |
| Open or closed system | Closed | Open |
| Results | Qualitative | Qualitative |
| Footprint size | Small | Moderate |
| List price per instrument ($) | 39,500 | 37,000 |
| List price reagent cost per specimen ($) | 155 | 80–90 |
a
RUO, research use only.