TABLE 3.
Association of resistance to amikacin and/or methicillin relative to resistance to other antimicrobials in Staphylococcus pseudintermedius isolatesa
| Antimicrobial agentb | No. (%) of isolates that werec: |
Odds ratio (95% CI) | P | |
|---|---|---|---|---|
| AR and MR | AR or MR | |||
| Chloramphenicol | ||||
| S | 14 (22) | 50 (78) | 1 (NAd) | |
| R | 17 (40) | 25 (60) | 4.9 (1.2–4.9) | 0.0444 |
| Clindamycin | ||||
| S | 1 (5) | 21 (95) | 1 (NA) | |
| R | 30 (36) | 54 (64) | 11.6 (1.5–85.7) | 0.0177 |
| Doxycycline | ||||
| S | 5 (22) | 18 (78) | 1 (NA) | |
| R | 25 (31) | 56 (69) | 1.6 (0.5–4.8) | 0.3986 |
| Enrofloxacin | ||||
| S | 2 (5) | 35 (95) | 1 (NA) | |
| R | 29 (42) | 40 (58) | 12.7 (2.8–56.9) | 0.0012 |
| Erythromycin | ||||
| S | 1 (4) | 22 (96) | 1 (NA) | |
| R | 30 (37) | 51 (63) | 12.9 (1.8–95.0) | 0.0135 |
| Gentamicin | ||||
| S | 0 (0) | 38 (100) | 1 (NA) | |
| R | 31 (46) | 37 (54) | Inestimablee | <0.0001e |
| Marbofloxacin | ||||
| S | 8 (17) | 40 (83) | 1 (NA) | |
| R | 23 (40) | 34 (60) | 3.4 (1.3–8.5) | 0.0112 |
| Rifampin | ||||
| S | 1 (29) | 65 (71) | 1 (NA) | |
| R | 4 (31) | 5 (69) | 1.1 (0.3–3.8) | 0.9163 |
| Trimethoprim/sulfonamide | ||||
| S | 0 (0) | 26 (100) | 1 (NA) | |
| R | 31 (40) | 47 (60) | Inestimablee | 0.0003e |
a
n = 106.
b
S, susceptible; R, resistant.
c
AR and MR, isolates resistant to amikacin and oxacillin; AR or MR, isolates resistant to amikacin or oxacillin.
d
NA, not applicable (reference category).
e
Inestimable because of complete separation (no observations in one category); the P value was derived from the chi-square test with continuity correction.