FIG 2.

Leishmania interferes with expression of CD4, CD8, and Foxp3 receptors in the intestine and lymph nodes in dogs naturally infected with Leishmania infantum. (A) Gating strategies demonstrating fluorescence profiles of colonic lamina propria cells. The bar charts show frequencies of lymphocytes and CD4⁺, CD4⁺ Foxp3⁺, and CD8⁺ cells in intestinal tissue. (B) Gating strategies demonstrating fluorescence profiles of mesenteric and cervical lymph node cells. The bar charts show frequencies of lymphocytes and CD4⁺, CD4⁺ Foxp3⁺, and CD8⁺ cells in intestinal tissue. *, P < 0.05; **, P < 0.005; ***, P < 0.0005.