FIG 7.

Cytokine and chemokine levels are higher in lungs of infected pendrin KO mice. (A) Pendrin-expressing and pendrin KO mice (n = 4) were infected with B. pertussis, and at 4 dpi lung cytokine gene mRNA levels were analyzed by RT Array (see Table S1 in the supplemental material for full data); those genes whose expression was significantly different in pendrin KO mice than in pendrin-expressing mice are displayed. (B) Protein levels for the indicated cytokines in BAL fluid were measured by ELISArray. *, P < 0.05; **, P < 0.01; ***, P < 0.001 (relative to levels in infected pendrin-expressing mice).