FIG 3.
Kinetics of bacterial burden in mice infected orally with Y. pseudotuberculosis PB1+, χ10057(pYA3332), or χ10057(pYA5199). Groups of mice were inoculated orally with 0.7 × 109 CFU of wild-type Y. pseudotuberculosis PB1+, 1.5 × 109 CFU of χ10057(pYA3332), or 1.3 × 109 CFU of χ10057(pYA5199). CFU counts per organ in Peyer's patches (A), spleens (B), and livers (C) from 3 mice per group were determined at various times (3, 6, and 9 days). Error bars represent standard deviations. *, P < 0.05; **, P < 0.01; ***, P < 0.001; ns, not significant. The experiment was performed twice with similar results, and the results were pooled for presentation.