TABLE 4.
Infectivity of B. burgdorferi bb0238 TPR mutants in C3H/HeN mice
| Strain | No. of positive cultures/total |
No. positive mice/total | ||||||
|---|---|---|---|---|---|---|---|---|
| Ear punch | Back skin | Lymph nodesa | Heart | Tibiotarsal tissue | Bladder | All sites | ||
| Bb297 | 5/5 | 5/5 | 5/5 | 5/5 | 5/5 | 5/5 | 30/30 | 5/5 |
| BbΔbb0238 | 0/5b | 5/5 | 5/5 | 1/5b | 3/5 | 0/5b | 14/30b | 5/5 |
| Bbbb0238C | 5/5 | 5/5 | 5/5 | 5/5 | 5/5 | 5/5 | 30/30 | 5/5 |
| Bbbb0238Y43A | 0/5b | 3/5 | 1/5b | 1/5b | 3/5 | 0/5b | 8/30b | 4/5 |
| Bbbb0238Y50A | 0/5b | 3/5 | 5/5 | 5/5 | 3/5 | 2/5 | 18/30b | 5/5 |
| Bbbb0238A66G | 0/5b | 2/5 | 2/5 | 0/5b | 3/5 | 1/5b | 8/30b | 3/5 |
| Bbbb0238P71A | 0/5b | 3/5 | 2/5 | 0/5b | 3/5 | 1/5b | 9/30b | 4/5 |
a
A single brachial and inguinal lymph node were collected from each mouse and cultured together.
b
Statistically significant difference relative to Bbbb0238C (P < 0.05).