TABLE 1.
FIN biofilm sMICs for C. albicans isolates
| C. albicans strain | Prevention sMICs (mg/liter)a |
Treatment sMICs (mg/liter) |
||
|---|---|---|---|---|
| MIC90 | MIC50 | sMIC90 | sMIC50 | |
| SC5314 | 128 | 16 | >256 | 128 |
| 42379 | >256 | >256 | >256 | >256 |
| 53264 | 128 | 16 | >256 | 256 |
| UI3 | 256 | 64 | >256 | >256 |
| UI5 | >256 | 32 | >256 | >256 |
| UI6 | >256 | 128 | >256 | >256 |
| UI8 | >256 | 64 | >256 | >256 |
a
Sessile MIC50 (sMIC50) and sMIC90 values were defined as the lowest concentrations of FIN that inhibited 50% XTT reduction (50% biofilm metabolic activity) and 90% XTT reduction (10% biofilm metabolic activity) for the prevention of biofilm formation or treatment of mature biofilms, respectively.