TABLE 2.
Major outcomes of the three therapies
Outcome characteristic | Rate (% [no./total no.]) (95% CI) |
||
---|---|---|---|
Standard triple therapy (n = 103) | Sequential therapy (n = 102) | Concomitant therapy (n = 102) | |
Eradication rate | |||
Intention-to-treat | 81.6 (84/103) (74.1–89.0) | 89.2 (91/102) (83.2–95.2) | 94.1 (96/102) (89.5–98.7)a |
Per-protocol | 82.2 (83/101) (74.8–89.6) | 90.0 (90/100) (84.1–95.9) | 94.1 (96/102) (89.5–98.7)a |
Adverse events | 8.7 (9/103) (3.3–14.2) | 8.8 (9/102) (3.3–14.3) | 13.7 (14/102) (7.0–20.4) |
Compliance | 99.0 (102/103) (97.1–100.9) | 98.0 (100/102) (95.3–100.7) | 100.0 (102/102) |
Significant difference compared with standard triple therapy.