FIG 1.

Patient enrollment and treatment group assignment. Among 77 patients with TBM, 29 were excluded, as they did not meet the criteria; they died, lacked one of three lumbar punctures, or had an uncertain diagnosis. Among the remaining 48 patients with TBM, 15 were excluded due to mild grade I disease. Thirty-three patients with grade II/III TBM were assigned to the background regimen group (17 patients) or the linezolid-plus-background-regimen group (16 patients). Three lumbar punctures were performed, one at tuberculous meningitis diagnosis, one 2 weeks after treatment, and one 4 weeks after treatment. TB, tuberculosis; TBM, tuberculous meningitis.